ESCITALOPRAM CAPSULES 15 MG: Simple savings with less effort
Eligible, commercially insured patients could pay as little as $10 per month, automatically applied at the pharmacy, no copay card necessary. It’s that simple.
Automatic savings at the pharmacy counter with an eVoucher*
Eligible, commercially insured patients enjoy automatic savings at over 50,000 pharmacies nationwide. Copay savings are automatically applied at the pharmacy counter, without any action required by the patients.
The Vision of Almatica
We are committed to helping people live healthier lives through proven science by providing access to key Central Nervous System (CNS) products that address mental health and neurologic conditions.
*Escitalopram eVoucher Program Terms and Conditions:
The Almatica Escitalopram eVoucher Program helps commercially insured individuals who are permanent residents of the United States (including the United States Territories) and who are prescribed/dispensed Almatica-labeled Escitalopram Capsules for a use approved by the Food and Drug Administration pay for their eligible co-pay for Almatica-labeled Escitalopram Capsules. Under the program, eligible commercially insured patients may pay as little as $10 per 30-day supply of Almatica-labeled Escitalopram Capsules. A maximum savings limit per 30-day supply applies. The eVoucher automatically applies at over 50,000 pharmacies nationwide without any action required by patients. Patients with drug coverage under Medicare, Medicaid or TRICARE are not eligible for the Almatica Escitalopram eVoucher Program. Furthermore, patients residing in any state where such assistance is prohibited by law are not eligible for the Almatica Escitalopram eVoucher Program. This offer is void if copied, transferred, purchased, altered, or traded. The Almatica Escitalopram eVoucher Program is not insurance. Almatica reserves the right to change, rescind, revoke, or discontinue the program at any time without notice. Limit one program enrollment per individual. If you have any questions regarding this program, your eligibility, or benefits or if you wish to discontinue your participation in the program, please call 844-889-8686, option 1.
Considering which patients are appropriate for a 15 mg dose of escitalopram?1
For the treatment major depressive disorder (MDD) in adults younger than 65 years of age and pediatric patients 12 years of age and older.
For the treatment of generalized anxiety disorder (GAD) in adults younger than 65 years of age.
Contraindications
Escitalopram is contraindicated in patients
concomitantly using a monoamine oxidase inhibitor (MAOI) or within 14 days of stopping an MAOI,
concomitantly using pimozide,
with a known hypersensitivity to escitalopram or citalopram or any inactive ingredient in Escitalopram Capsules.
Warnings and precautions
Serotonin Syndrome: Escitalopram can precipitate serotonin syndrome, a potentially life-threatening condition. The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. John’s Wort) and with drugs that impair metabolism of serotonin, i.e., MAOIs. Serotonin syndrome can also occur when these drugs are used alone.
Discontinuation Syndrome: Adverse reactions after discontinuation of serotonergic antidepressants, particularly after abrupt discontinuation, include: nausea, sweating, dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesia, such as electric shock sensations), tremor, anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, tinnitus, and seizures. A gradual reduction in dosage rather than abrupt cessation is recommended whenever possible.
Seizures: In clinical trials of another escitalopram product, cases of convulsion have been reported in association with escitalopram treatment. Like other drugs effective in the treatment of MDD, Escitalopram Capsules should be introduced with care in patients with a history of seizure disorder.
Activation of Mania or Hypomania: In patients with bipolar disorder, treating a depressive episode with Escitalopram Capsules or another antidepressant may precipitate a mixed/manic episode.
Hyponatremia: Hyponatremia may occur as a result of treatment. In many cases, this hyponatremia appears to be the result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and was reversible when escitalopram was discontinued. Cases with serum sodium lower than 110 mmol/L have been reported with another escitalopram product. Geriatric patients may be at greater risk of developing hyponatremia with SSRIs and SNRIs (Escitalopram Capsules are not indicated in geriatric patients). Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. Consider discontinuing Escitalopram Capsules in patients with symptomatic hyponatremia and institute appropriate medical intervention.
Increased Risk of Bleeding: Escitalopram Capsules increase the risk of bleeding events. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may add to the risk. Case reports and epidemiological studies (case-control and cohort design) have demonstrated an association between use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleeding. Based on data from the published observational studies, exposure to SSRIs, particularly in the month before delivery, has been associated with a less than 2-fold increase in the risk of postpartum hemorrhage. Bleeding events related to drugs that interfere with serotonin reuptake have ranged from ecchymoses, hematomas, epistaxis, and petechiae to life-threatening hemorrhages.
Interference with Cognitive and Motor Performance: Because any psychoactive drug may impair judgment, thinking, or motor skills, patients should be cautioned about operating hazardous machinery, including automobiles, until they are reasonably certain that Escitalopram Capsules do not affect their ability to engage in such activities.
Angle Closure Glaucoma: The pupillary dilation that occurs following use of many antidepressant drugs, including Escitalopram Capsules, may trigger an angle closure attack in a patient with anatomically narrow angles who does not have a patent iridectomy. Avoid use of antidepressants, including Escitalopram Capsules, in patients with untreated anatomically narrow angles.
Use in Patients with Concomitant Illness: Caution is advisable in using escitalopram in patients with diseases or conditions that produce altered metabolism or hemodynamic responses.
In subjects with hepatic impairment, clearance of racemic citalopram was decreased and plasma concentrations were increased. Escitalopram Capsules are not recommended in patients with hepatic impairment.
Pharmacokinetics of escitalopram in patients with a creatinine clearance less than 20 mL/minute has not been evaluated, however, it should be used with caution in such patients.
Sexual Dysfunction: Use of SSRIs, including Escitalopram Capsules, may cause symptoms of sexual dysfunction. In male patients, SSRI use may result in ejaculatory delay or failure, decreased libido, and erectile dysfunction. In female patients, SSRI use may result in decreased libido and delayed or absent orgasm.
Adverse reactions
The most common adverse reactions in clinical trials included: insomnia, ejaculation disorder (primarily ejaculatory delay), nausea, increased sweating, fatigue and somnolence, decreased libido, and anorgasmia.
Select use in specific populations
Pregnancy
Consider the risk of untreated depression when discontinuing or changing treatment with antidepressant medication during pregnancy and postpartum.
Use of Escitalopram Capsules in the month before delivery may be associated with an increased risk of postpartum hemorrhage.
Neonates exposed to SSRIs or SNRIs, including Escitalopram Capsules, late in third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. Such complications can arise immediately upon delivery.
Lactation
Infants exposed to Escitalopram Capsules should be monitored for excess sedation, restlessness, agitation, poor feeding and poor weight gain.
Pediatric Use
The safety and effectiveness of Escitalopram Capsules for the treatment of MDD have not been established in pediatric patients younger than 12 years of age.
Hepatic Impairment
Escitalopram Capsules are not recommended in patients with hepatic impairment.
